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华盛顿大学: 青蒿素加高压氧 对癌细胞的选择性是化疗药的100倍

University of Washington Hpyerbaric Oxygen Enhances Artemisinin's Cancer-Killing selectivity 100 times more than chemo

Victor Marchione博士,MD - 2011年4月13日

一项新的健康突破发现,将高压氧与天然药物青蒿素结合可能为杀死癌细胞提供新的途径。

一项新的健康突破发现,高压氧与天然药物“青蒿素”的结合可能为杀死癌细胞提供新的途径。研究人员发现,这种组合可以减少38%的癌细胞生长。对于那些患有癌症的人来说,这是一大健康新闻。

青蒿素是从青蒿中提取的化合物,广泛用于治疗疟疾。在20世纪90年代中期,研究人员开始探索它对癌症的作用。一项新的研究发现,纯氧环境在正常空气压力的三倍以上,可以显著提高青蒿素的有效性。

在这项新的研究中,单独使用青蒿素或高压氧治疗人类白血病细胞,癌细胞的生长减少了15%。但结合使用它们,这一增幅进一步下降至38%。这不仅仅是青蒿素的有效性增加了50%。这显然是一种更好的治疗效果,在48小时内就被发现。研究人员说,在更长一段时间内,结果可能会更加引人注目。

青蒿素被认为有用于医学的历史,可以追溯到几千年前的中国古代。它的现代应用是在亚洲和非洲的疟疾治疗。但在过去的几十年里,科学家们做到了。

发现青蒿素与细胞内的铁发生反应,形成自由基。这种高度反应性的粒子可以破坏细胞。这通常对我们来说是件坏事,但对于癌细胞来说,这显然是积极的。

快速分裂的癌细胞也需要铁来形成新的DNA。研究人员认为,他们还将为青蒿素靶向目标。这种天然的治疗方法是一种价格低廉、潜力巨大的癌症治疗方法。根据研究人员的说法,青蒿素在治疗上的特异性是化学疗法的100倍。化学疗法本质上是将身体的整个区域炸成碎片,希望杀死体内的癌细胞。

对氧的看法是,高水平会增强青蒿素的作用,因为氧促进自由基的形成。2010年,一名研究人员在高压氧气室放置了一个带有人类癌细胞的培养皿,为期两天。这导致了新的结果,这可能会进一步研究高压氧舱如何使癌症治疗更有效。

The Newest Cancer Fighter Revealed

By Dr. Victor Marchione, MD - April 13, 2011

Disclaimer: Results are not guaranteed*** and may vary from person to person***.

A new health breakthrough has found that combining high-pressure oxygen with the natural remedy artemisinin may provide a new avenue for killing cancer cells. Researchers have found that the combination could reduce the growth of cancer cells by 38%. And for those who live with cancer, this is a great dose of health news.A new health breakthrough has found that combining high-pressure oxygen with the natural remedy “artemisinin” may provide a new avenue for killing cancer cells. Researchers have found that the combination could reduce the growth of cancer cells by 38%. And for those who live with cancer, this is a great dose of health news.

Artemisinin is a compound from wormwood and is widely used to treat malaria. In the mid-1990s, researchers began exploring its actions on cancer. A new study has found that an environment of pure oxygen at over three times the normal air pressure could significantly boost the effectiveness of artemisinin.

In the new study, using artemisinin or high-pressure oxygen alone on human leukemia cells reduced the cancer cells’ growth by 15%. But using them in combination further dropped that growth to 38%. That is more than a

50% increase in artemisinin’s effectiveness. This is clearly a much better curing effect, and it was seen in just 48 hours. Over longer periods of time, the researchers say the results could be more dramatic.

Artemisinin is believed to have a history of being used in medicine that dates back thousands of years to ancient China. Its modern use is in malaria treatment in Asia and Africa. But in the past few decades, scientists have

discovered that artemisinin reacts with iron within a cell to form a free radical. This highly reactive particle can act to destroy the cell. This is normally a bad thing for us, but in the case of cancer cells, it is obviously quite positive.

Rapidly dividing cancer cells also need iron to form new DNA. The researchers believed they would also make targets for artemisinin. This natural remedy is an inexpensive and potentially quite promising cancer treatment. According to the researchers, artemisinin is 100 times more specific in its treatment than chemotherapy, which essentially carpet-bombs an entire area of the body in hopes that it kills the cancer cells there.

The idea with oxygen is that high levels would boost artemisinin because oxygen promotes the formation of free radicals. In 2010, a researcher placed a Petri dish with human cancer cells in a high-pressure oxygen chamber for two days. That led to the new results, which may lead to further looks at how hyperbaric chambers could make cancer treatments more effective.

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